<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TK3037 TK3037 Denmark 2002 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT+ RTV 196

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       K32R, V35T, K49R, K122E, D123E, I135T, T165I, D177E, I178V, T200A, I202V, Q207E, R211K, F214L, V245E, D250E, A272P, K277R, T286A A129AG
>TK3037| codons 1-312
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTGFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPEVVI
YQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A   L10V, T12TA, I13V, K14R, G16A, R41K, K43R, I62V, L63P, A71T  
>TK3037| codons 1-99
PQITLWQRPVVAVRIAGQLKEALLDTGADDTVLEEMNLPGKWRPKMIGGIGGFVKVRQYD
QVPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005