Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3036 | TK3036 | Denmark | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ EFV | 1 |
| 2 | None | 7 |
| 3 | ABC+ D4T+ EFV | 100 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, E35D, M36I, N37E, R41K, R57K, H69K, K70R, L89M |
| >TK3036| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDIELPGKWKPKMIGGIGGFIKVKQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | D67G, K219Q | K103N, G190A | V35T, K49R, E53D, V60I, D121H, K122E, I135T, K173S, Q174K, D177E, T200A, Q207G, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, Q334R |
| >TK3036| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPDNPYNTPI FAIKKKGSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIVI YQYMDDLYVASDLEIGQHRAKIEELRGHLLKWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGR |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |