Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3031 | TK3031 | Denmark | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ SQV | 121 |
| 2 | D4T+ DDI+ NFV+ NVP | 82 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K103N | V35VI, T39D, V90VI, V118I, K122E, I135T, K173T, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, R284K, T286A, E291D, V292I, I293V, E297K |
| >TK3031| codons 1-323 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICDELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGAKALTDIVPLTKEAE LELAENREILKEPVHGVYYDPSK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I15V, L19I, K20T, E35G, M36I, R41K, L63S, H69K, T74A, L89M, I93L | G51GR |
| >TK3031| codons 1-99 PQITLWQRPLVTIKVGGQITEALLDTGADNTVLEGINLPGKWKPKMIGGIRGFIKVRQYD QISIEICGKKAIGAVLVGPTPVNIIGRDMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |