Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3030 | TK3030a | Denmark | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ SQV | 89 |
| 2 | AZT+ DDI+ NFV | 223 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IL, L90LM | I13V, K20RT, E35D, M36I, N37NT, R41K, K45KR, R57K, H69K, A71AV, L89I, I93IM |
| >TK3030a| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDITLPGKWKPRMIGGIGGFLKVKQYD QILIEICGKKVIGTVLVGPTPVNIIGRNIMTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, K70R | D67DG, T215TI, K219Q | V35T, T39I, V60I, K64KN, T69N, D121Y, K122E, I135T, K173S, Q174K, D177E, V179I, Q197E, Q207A, R211NS, V245K, D250E, A272T, T286A, I293V, P294T, L295LM, E312D |
| >TK3030a| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICIELEKEGKISKIGPENPYNTPI FAINKKGSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIGEHRTKIEELRAHLLNWGFITPDQKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYTGIKVKQLCKLLRGAKALTEVVTMTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |