Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3029 | TK3029a | Denmark | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ SQV | 106 |
| 2 | D4T+ DDI+ NFV | 26 |
| 3 | D4T+ NFV+ 3TC | 17 |
| 4 | D4T+ ABC+ EFV | 59 |
| 5 | D4T+ ABC+ 3TC | 10 |
| 6 | D4T+ ABC+ 3TC+ LPV | 58 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, T7S, V35T, K49R, V60I, V90I, K122E, D123S, I135T, S162D, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, A272G, T286A, E291D, I293V, P294T | T131TA |
| >TK3029a| codons 1-301 PISPIDSVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFAIPSTNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYGGIKVKQLCKLLRGAKALTDVVTLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, H69K, L89M |
| >TK3029a| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |