Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3026 | TK3026 | Denmark | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ RTV | 35 |
| 2 | 3TC+ D4T+ SQV | 50 |
| 3 | 3TC+ D4T+ NFV | 207 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V35T, E36A, T39E, S48T, K122E, I135T, K173A, Q174K, D177E, T200A, E203K, Q207E, R211RK, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, D324E, G333E, Q334H |
| >TK3026| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQEHG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I15V, L19I, K20T, E35D, M36I, R41RK, L63P, H69K, A71I, T74S, L89I, I93L |
| >TK3026| codons 1-99 PQITLWQRPLVTIKVGGQITEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKIIGSVLVGPTPVNIIGRNIMTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |