Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3024 | TK3024 | Denmark | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ SQV | 76 |
| 2 | D4T+ DDI+ NFV | 129 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215Y | K22X, V35T, E36A, T39E, S48T, V118VI, K122E, K166R, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I | K13KM, L26LF |
| >TK3024| codons 1-324 PISPIETVPVKLMPGMDGPKVXQWPFTEEKIKALTAICEELEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, L63P, H69K, A71I, T74S, I93L |
| >TK3024| codons 1-99 PQITLWQRPLVSIKVGGQITEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKIIGSVLVGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |