Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3020 | TK3020 | Denmark | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ RTV | 57 |
| 2 | 3TC+ D4T+ NFV | 14 |
| 3 | 3TC+ D4T+ SQV | 18 |
| 4 | D4T+ SQV+ DDI | 31 |
| 5 | DDI+ ABC+ EFV | 17 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R41K, L63AT, H69K, T74S, L89I, I93L |
| >TK3020| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIAIEICGKKAIGSVLVGPTPVNIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, L74V | K219Q | G190GE | V35T, E36A, T39E, S48T, V60I, K122E, D123N, I135T, S162Y, K173A, Q174K, D177E, V179VA, T200A, E203K, Q207E, R211K |
| >TK3020| codons 1-219 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRAKNPEIAI YQYMDDLYVESDLEIGQHRAKIKELREHLLKWGFTTPDQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |