Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3017 | TK3017a | Denmark | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ RTV | 222 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, L63T, H69K, L89M |
| >TK3017a| codons 1-99 PQITLWQRPVVTVKIEGQLREALLDTGADDTVLEDINLSGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K11T, V21I, V35T, T39A, E40D, I135V, K173A, Q174K, D177E, V179I, I202V, Q207A, R211K, V245Q, T286A, E291D, I293V, E312D |
| >TK3017a| codons 1-324 PISPIETVPVTLKPGMDGPKIKQWPLTEEKIKALTEICADMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIII YQYVDDLYVGSDLEIGQHRTKVEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVPLTEEAE LELAENREILKDPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |