<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TK3015 TK3015 Denmark 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT+ SQV 43
2 AZT+ DDC+ IDV 161

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y       V35M, T39D, E44D, V118I, K122E, I135L, K173A, Q174K, N175Y, D177E, V179A, E194K, G196E, T200A, I202V, Q207E, R211K, V245Q, D250E, I257V, A272S, T286A, K287X, E291D, V292I, I293V, H315F  
>TK3015| codons 1-324
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICDELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKYPEIAI
YQYMDDLYVGSDLKIEQHRAKVEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDVQKLVGKLNWASQIYSGIKVKQLCKLLRGANALTDIVPLTEEAE
LELAENREILKEPVFGVYYDPSKD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M K43T L10I, T12S, I15V, L19I, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93L  
>TK3015| codons 1-99
PQITLWQRPIVSIKVGGQIIEALLDTGADDTVLEDINLPGKWTPKMIGGIGGFVKVRQYE
EIPIEICGKKVIGTVLVGPTPANIVGRNLMTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005