Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3011 | TK3011 | Denmark | 2001 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ SQV | 94 |
| 2 | 3TC+ D4T+ NFV | 137 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V35ST, V60I, D121Y, K122E, D177E, I178M, T200I, Q207E, R211K, V245E | L34LPS |
| >TK3011| codons 1-245 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKASTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYVDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I13V, I15V, K20T, E35D, M36I, N37NY, R41K, I64V, T74S |
| >TK3011| codons 1-99 PQITLWQRPLVTVKVGGQLTEALLDTGADNTVLEDIYLPGKWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGSVLVGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |