Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3007 | TK3007c | Denmark | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | ABC+ D4T+ DDI | 12 |
| 2 | None | 9 |
| 3 | 3TC+ AZT+ IDV+ RTV | 58 |
| 4 | 3TC+ AZT+ EFV | 46 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N83ND, L89MV | T12S, I15V, L19IM, E34A, M36I, R41K, L63P, H69K, I93L |
| >TK3007c| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLAEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVDIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101E, V106M | F227FL | E28A, V35T, T39A, S48T, R83RK, K122E, D123S, S162A, K173T, D177E, T200A, Q207E, P243T, V245Q, E291D, V292I, I293V |
| >TK3007c| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALTEICAEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLEKKKSMTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPLLWMGYELHPDKWT VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |