<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TK3007 TK3007b Denmark 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 ABC+ D4T+ DDI 12
2 None 9
3 3TC+ AZT+ IDV+ RTV 58
4 3TC+ AZT+ EFV 33

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101E, V106M   E28A, V35T, T39AV, S48T, K122E, D123S, S162AD, K173T, D177E, T200A, Q207E, P243T, V245Q, E291D, V292I, I293V, E312EG  
>TK3007b| codons 1-324
PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALTEICAEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKGPVHGVYYDPSKD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19M, E34A, M36I, R41K, L63P, H69K, L89M, I93L  
>TK3007b| codons 1-99
PQITLWQRPLVSIKVGGQMKEALLDTGADDTVLAEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005