Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3006 | TK3006a | Denmark | 2001 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ RTV | 177 |
| 2 | D4T+ NFV+ NVP | 17 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | T27S, V35T, V60I, D121Y, K122E, I135T, T139TI, D177E, T200I, Q207E, R211K, F214L, H221HY, V245E, D250E, A272P, K277R, L282C, L283I, R284K | P52PL, L303LR |
| >TK3006a| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICTEMEKEGKISKIGLENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNEIPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGLTTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIKGTKALTEVIPLTEEAE LERAENREILKEPVHGVYYD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82F, L90M | L33F | I13V, I15V, R41K, I64V |
| >TK3006a| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVFEEMNLPGKWKPKMIGGIGGFVKVRQYD QILVEICGHKAIGTVLVGPTPFNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |