Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK3003 | TK3003 | Denmark | 2002 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ SQV | 85 |
| 2 | 3TC+ AZT+ NFV+ NVP | 162 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | K20T, E35D, M36I, N37DE, R41K, D60E, I62V, L63S, I64V, V77VI, V82I |
| >TK3003| codons 1-99 PQITLWQRPLVTIKIGGQLTEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVRQYE QVSVEICGHKAIGTVLIGPTPINIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | V35T, K49R, V60I, K102R, I135T, Q174R, D177E, I178M, T200M, Q207E, R211K, F214FL, L228LH, V245K, D250E, A272P, L282C |
| >TK3003| codons 1-285 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPEMVI YQYVDDLYVGSDLEIGQHRMKIEELREHLLKWGLTTPDKKHQKEPPFHWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKCLRG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |