Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2027 | TK2027 | Denmark | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV | 49 |
| 2 | 3TC+ AZT+ IDV+ RTV | 41 |
| 3 | 3TC+ AZT+ EFV | 78 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, K45R, R57K, H69K, L89M |
| >TK2027| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | V35K, T39A, I142T, K173S, Q174K, D177E, V179I, I202V, Q207A, R211S, E248D, D250E, S251D, K281R, T286A, V292R, I293V, P294T, E312D |
| >TK2027| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYVDDLYVGSDLEIGQHRTKVEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKEDWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTERVTLTEEAE LELAENREILKDPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |