Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2025 | TK2025 | Denmark | 2000 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ IDV | 8 |
| 2 | None | 31 |
| 3 | 3TC+ D4T+ IDV | 25 |
| 4 | IDV | 7 |
| 5 | 3TC+ ABC+ D4T+ RTV | 1 |
| 6 | 3TC+ ABC+ D4T+ RTV+ NVP+ SQV | 5 |
| 7 | None | 3 |
| 8 | 3TC+ ABC+ D4T+ NVP+ RTV+ SQV | 105 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V | K101E, Y181C, G190A | K32R, V35M, E42EG, K43N, V60I, K122E, I135T, D177E, T200I, Q207E, R211K, V245EK, D250E, A272P, L282C, R284K, T286A, I293V, E297A |
| >TK2025| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALMEICTEMGNEGKISKIGPENPYNTPI FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYVDDLYVASDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKCLKGAKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |