Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2024 | TK2024 | Denmark | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ IDV | 48 |
| 2 | None | 13 |
| 3 | 3TC+ D4T+ IDV | 72 |
| 4 | 3TC+ IDV+ AZT+ DDI+ EFV+ RTV | 91 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35DN, M36I, N37DE, P39PS, R41K, H69K, L89M |
| >TK2024| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDIDLSGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V | V35T, E36D, T39E, W88C, K122E, D123S, E138A, K173T, D177E, I178L, T200A, Q207K, H208Y, R211K, V245Q, L246X, A272P, K275R, V292I, I293V, V317A, D320DE |
| >TK2024| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICEELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPELVI YQYVDDLYVGSDLEIGQHRAKIEELRKYLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQXPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEIVPLTEEAE LELAENREILKEPVHGAYYEPSKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |