Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2021 | TK2021 | Denmark | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 88 |
| 2 | 3TC+ AZT+ EFV | 85 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, E35D, M36I, R41K, R57RK, H69K, K70R, L89M |
| >TK2021| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | P225PH, K238KT | V35T, E40D, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, V189VI, I202V, Q207A, R211S, F214L, V245E, D250E, L283I, V292I, I293V, E312N | Q23QH |
| >TK2021| codons 1-320 PISPIETVPVKLKPGMDGPKVKHWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYVDDLYIGSDLEIGQHRTKVEELRAHLLSWGLTTPDKKHQKEHPFLWMGYELHPDTWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKALTEIVPLTEEAE LELAENREILKNPVHGVYYD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |