Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2019 | TK2019 | Denmark | 2001 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 61 |
| 2 | 3TC+ D4T+ RTV+ SQV | 46 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, M36I, N37DE, R41K, H69K, K70R, T74S, L89M |
| >TK2019| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGSVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K64R, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, S322A | K277KE, K281I |
| >TK2019| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVEQLCILLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |