Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2016 | TK2016 | Denmark | 2003 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 4 |
| 2 | AZT | 43 |
| 3 | AZT+ 3TC | 4 |
| 4 | AZT+ 3TC+ IDV | 91 |
| 5 | AZT+ 3TC | 4 |
| 6 | 3TC+ D4T+ NFV+ NVP | 186 |
| 7 | 3TC+ D4T+ NVP | 13 |
| 8 | 3TC+ D4T+ NFV | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181C | V35T, S48A, K49R, V60I, D121Y, K122E, T165TA, D177E, I178M, T200I, I202V, Q207G, R211K, V245E, D250E, A272P, K277R, L282C, T286A, I293V, K323Q | S163SN |
| >TK2016| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIARIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSNMAKILEPFRKQNPEMVI CQYVDDLYVGSDLEIGQHRIKVEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCLRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSQDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, M36I, R41K, I64V |
| >TK2016| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |