Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2015 | TK2015 | Denmark | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ RTV | 107 |
| 2 | None | 1 |
| 3 | 3TC+ D4T+ NFV+ NVP | 178 |
| 4 | None | 3 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | P4S, V35T, E36A, T39D, S48T, K122E, D123G, S162Y, K173A, Q174K, D177E, V179I, I195L, G196M, T200A, Q207E, R211K, V245Q, D250DE, A272P, E291D, V317A, D320X, P321X, S322SL, K323X | P225PL |
| >TK2015| codons 1-324 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRAKNPEIII YQYVDDLYVGSDLELMQHRAKIEELREHLLKWGFTTPDKKHQKELPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVIPLTEEAE LELAENREILKEPVHGAYYXXLXD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LV, I15V, L19I, M36I, R41K, H69K, I93L |
| >TK2015| codons 1-99 PQITLWQRPVVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |