<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TK2009 TK2009 Denmark 2002 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I15V, M36I, R41K, D60E, I62V, L63T, I64V, I72T  
>TK2009| codons 1-99
PQITLWQRPLVAIKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
QVTVEICGHKATGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40D, V60I, D121Y, K122E, D177E, T200R, Q207G, R211K, K238R, V245E, D250E, A272PS, K275Q, K277R, Q278QH, L282C, T286A, I293V, P294A  
>TK2009| codons 1-321
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRRKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIQVRHLCKCLRGAKALTEVVALTEEAE
LELAENREILKEPVHGVYYDP

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005