Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2005 | TK2005 | Denmark | 2001 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ RTV | 13 |
| 2 | 3TC+ D4T+ IDV | 122 |
| 3 | 3TC+ ABC+ DDI+ EFV | 119 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV | K20KT, R41K, L63P, I64V, T74TS, V82I |
| >TK2005| codons 1-99 PQITLWQRPLVTIKIGGQLTEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFVKVRQYD QIPVEICGHKAIGSVLVGPTPINIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70KR, L74V, M184V | K219Q | L100I, K103N | V35T, K49R, V60I, K102E, D121DY, K122KE, I135T, T139K, S162Y, D177E, V189I, I202V, Q207E, R211K, T215X, L228H, V245K, D250E, A272P, K277R, L282C, L283I, T286A, A288T, I293V, E297K | T253N |
| >TK2005| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKENKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNEKPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPEIVI YQYVDDLYIGSDLEIGQHRTKVEELREHLLKWGFXTPDQKHQKEPPFHWMGYELHPDKWT VQPIKLPEKESWNVNDIQKLVGKLNWASQIYPGIKVRQLCKCIRGAKTLTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |