Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK2002 | TK2002 | Denmark | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 215 |
| 2 | 3TC+D4T+IDV+RTV | 58 |
| 3 | ABC+AZT+EFV | 24 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, V21I, V35T, T39G, V60I, K122E, D123NS, I135T, K173S, Q174QK, D177E, V179I, T200A, I202V, Q207A, R211S, V245QR, E248C, S251C, T286A, E291D, I293V, P294T, G335D |
| >TK2002| codons 1-345 PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALTEICGEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIGQHRAKVEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPCKDCWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, V82AT | L33I, N83D | L10LI, I13V, K14R, A22AV, E35D, M36I, R41K, R57K, H69K, L89IM |
| >TK2002| codons 1-99 PQITLWQRPIVTVRIGGQLKEVLLDTGADDTVIEDINLPGKWKPKIIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPADIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |