Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK1030 | TK1030a | Denmark | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ RTV+ SQV | 62 |
| 2 | 3TC+ D4T+ RTV+ IDV | 33 |
| 3 | 3TC+ RTV+ IDV+ AZT+ DDI+ EFV | 210 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K103N | K20KR, V35T, V60I, K101KR, K122E, I135T, K173A, Q174K, D177E, V179I, T200A, I202IV, Q207A, R211X, F214FL, E248ED, D250E, T286A, K287R, E291D, V292I, I293V, E312D, D324E, I326V |
| >TK1030a| codons 1-334 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIII YQYVDDLYVGSDLEIGQHRAKVEELRAHLLXWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGARALTDIVPLTEEAE LELAENREILKDPVHGVYYDPSKELVAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, G16GE, E35D, M36I, R41K, R57K, L63PS, H69K, L89M |
| >TK1030a| codons 1-99 PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |