<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TK1023 TK1023 Denmark 2003 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LI, I13V, K14R, K20R, E21ED, E35D, M36I, N37D, R41K, R57K, I62V, H69K, T74S, L89M  
>TK1023| codons 1-99
PQITLWQRPIVTVRIGGQLRDALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD
QVLIEICGKKAIGSVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21VL, V35T, V60I, T69TS, K122E, D123S, I135T, S162CY, K173S, Q174K, D177E, V179I, G196E, T200TA, Q207A, R211S, V245Q, D250E, A272Q, K277KR, K281KR, T286A, E291D, V292VI, I293IV, P294PT, E312D, D324E, I329V  
>TK1023| codons 1-334
PISPIETVPVKLKPGMDGPKLKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRSKNPEIII
YQYMDDLYVGSDLEIEQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYQGIKVRQLCRLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPSKELIAEVQKQGQ

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005