Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK1007 | TK1007a | Denmark | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ EFV | 134 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67G, K219Q | K101E, G190S | E28G, V35T, T39E, E44D, V118I, K122E, D123N, I135T, I142V, K173L, V179I, T200A, Q207A, R211S, F214L, V245Q, K281R, E291D, I293V, E297K, E312D, S322A, D324E | K154KN, F160FS |
| >TK1007a| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTGEKIKALTEICEEMEKDGKISKIGPENPYNTPV FAIKKKGSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWNGSPAISQSSMTKILEPFRLQNPDIII YQYMDDLYVSSDLEIGQHRAKIEELRAHLLSWGLFTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTDVVPLTKEAE LELAENREILKDPVHGVYYDPAKELIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20R, M36I, R41K, H69K, L89M |
| >TK1007a| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |