Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE545 | SE545_7d | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 1 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106VA, Y181YC | K11T, K20R, V21I, V35T, T39R, V60I, D123N, T165I, K173S, D177E, V179I, G196E, I202V, Q207A, R211K, V245Q, E248D, S251I, K277R, T286A, E291D, P294T |
| >SE545_7d| codons 1-334 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DKNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRSQNPEIII CQYMDDLYVGSDLEIEQHRTKVEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDIWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDVITLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L33V, R41K, K45R, K55KR, L63P, H69K, L89M |
| >SE545_7d| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVVEEMNLPGKWKPRMIGGIGGFIRVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose nvp prophylaxis: HIVNET 012. | ARHR, 2004 |