Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE681 | SE681_7d | Uganda | 1998 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 1 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| Q7H, T12S, K14R, I15L, Q18L, M36I, R41K, L63S, H69K, L89M, I93L | R8L, G16V, D29A |
| >SE681_7d| codons 3-99 ITLWHLPLVSIRLVGLLKEALLDTGAADTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQI SIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V21I, K32KE, V35T, E36A, T39E, K122E, D123DG, A158S, K173T, D177E, T200A, Q207E, V245EQ, S251SI, K277R, T286A, E291D, V292I, I293V | V60VG |
| >SE681_7d| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIEALTAICEEMEKEGKISKIGPENPYNTPG FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDIWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Eshleman, SH | Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose nvp prophylaxis: HIVNET 012. | ARHR, 2004 |