<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SE681 SE681_7d Uganda 1998 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None 52
2 NVP 1
3 None 1

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q7H, T12S, K14R, I15L, Q18L, M36I, R41K, L63S, H69K, L89M, I93L R8L, G16V, D29A
>SE681_7d| codons 3-99
ITLWHLPLVSIRLVGLLKEALLDTGAADTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQI
SIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, K32KE, V35T, E36A, T39E, K122E, D123DG, A158S, K173T, D177E, T200A, Q207E, V245EQ, S251SI, K277R, T286A, E291D, V292I, I293V V60VG
>SE681_7d| codons 1-333
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIEALTAICEEMEKEGKISKIGPENPYNTPG
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRTQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDIWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Eshleman, SH Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose nvp prophylaxis: HIVNET 012. ARHR, 2004