Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMP003-73 | 03-73000 | U.S. | 1995 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | IDV+ EFV | 41 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | V108I | K173N, Q197E, R211G |
| >03-73000| codons 1-229 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRNQNPDIVI YQYMDDLYVGSDLEIGEHRTKIEELRQHLLGWGFTTPDKKHQKEPPFLW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I62V, L63P, V77I, I93L |
| >03-73000| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLIGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Bacheler, LT | Genotypic correlates of phenotypic resistance to Efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy. | J Virol, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |