Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMP003-26 | 03-26125 | U.S. | 1995 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | IDV+ EFV | 18 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | K103N, Y188L | K20KR, D121Y, K122E, E138A, S162C, T200A |
| >03-26125| codons 1-229 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLLVGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, V82A | E35D, N37D, L63P, A71V |
| >03-26125| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEDMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Bacheler, LT | Genotypic correlates of phenotypic resistance to Efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy. | J Virol, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |