Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| VL98SN53HALD | 98SN53 | Africa | 1998 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177E, T200A, Q207N, V245Q, D250G, A272P, K277R, T286A, E291D, V292I, I293V, I329L, G335D, R356K, G359T, A376T, T377M, T386A, A400T, T403M, E404D, E432D, D443N |
| >98SN53| codons 1-445 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRNHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKGSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKITMESIVIWGKAPKFKLPIQKETWETWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVNGA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, E35D, M36I, R41K, R57K, H69K, L89M |
| >98SN53| codons 1-99 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Vergne, L | Low rate of genotypic HIV-1 drug-resistant strains in the Senegalese government initiative of access to antiretroviral therapy. | AIDS, 2003 |