<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
VL98SN68HPD 98SN68 Africa 1998 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93V  
>98SN68| codons 12-99
TVRVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIPIEIEGKKA
IGTVLVGPTPINIIGRNMLTQVGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60I, A98S, D123E, K173T, Q174K, D177E, G196E, T200A, Q207E, R211K, V245Q, D250E, A272P, K275Q, E291D, V292I, I293V, E297A, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, E370D, A371V, A376S, T377M, T386I, K390R, Q394R, A400V, E404D, E413D, Q428R, K431T, E432D  
>98SN68| codons 1-433
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLRGTKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKELIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTDVVQKISMESIVIWGKIPKFRLPIRKETWEVWWTDYWQATWIPDWEFVNTP
PLVKLWYRLETDP

References
Author Title Citation
Vergne, L Low rate of genotypic HIV-1 drug-resistant strains in the Senegalese government initiative of access to antiretroviral therapy. AIDS, 2003