Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| VL98SN46HALD | 00SN46 | Africa | 2000 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ D4T+ IDV | NA |
| 2 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | K219E | V35T, T39L, V60I, K122P, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, D250E, A272P, T286A, E291D, V292I, I293V, P294T, E312G, S322A, G335D, R356K, M357R, R358S, G359S, Q367P, E370Q, A371V, I375V, A376S, T377L, S379C, K390R, K395R, T403M | N306D |
| >00SN46| codons 1-420 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAEDREILKGPVHGVYYDPAKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRSSA HTNDVKPLTQVVQKVSLECIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G17E, K20I, M36I, R41K, I64M, H69K, L89M |
| >00SN46| codons 1-99 PQITLWQRPLVTVRIGEQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILMEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Vergne, L | Low rate of genotypic HIV-1 drug-resistant strains in the Senegalese government initiative of access to antiretroviral therapy. | AIDS, 2003 |