Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| VL99SN74HALD | 99SN74-1 | Africa | 1999 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ D4T | NA |
| 2 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35L, E36D, S68N, V90I, K122Q, I135V, S162A, K166R, K173E, Q174R, D177E, T200A, Q207E, R211K, V245Q, A272V, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, M357R, R358K, G359S, A371V, I375V, T403M, E432D |
| >99SN74-1| codons 1-434 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLDICTEMEKEGKISKIGPENPYNTPV FAIKKKDNTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DQDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRERNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYVGIKVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARRKSA HTNDVKQLTEVVQKVATESIVIWGKTPKFKLPIQKETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13A, K20I, M36I, R41K, H69K, L89M |
| >99SN74-1| codons 1-99 PQITLWQRPLVTAKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Vergne, L | Low rate of genotypic HIV-1 drug-resistant strains in the Senegalese government initiative of access to antiretroviral therapy. | AIDS, 2003 |