Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| VL00SN101hald | 99SN101 | Africa | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L63A, Q92H |
| >99SN101| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIAIEICGHKAIGTVLVGPTPVNIIGRNLLTHIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| S162C, G196E, P243T, A272S, L283I, I329L, Q334N, R358K, A376S, T386I, K390R, A400I | Y146L |
| >99SN101| codons 1-435 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQLNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQTIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLIRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGNGQWTYQIYQEPFKNLKTGKYARMKGA HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWEIWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIV |
References
| Author | Title | Citation |
| Vergne, L | Low rate of genotypic HIV-1 drug-resistant strains in the Senegalese government initiative of access to antiretroviral therapy. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |