<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MSM_pat2 MLpat2_a Germany 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A, L90M Q58E L10I, I15V, K20R, M36I, R41K, K55R, R57K, I62V, L63P, A71V, L89M, I93M T74KR
>MLpat2_a| codons 1-99
PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEEINLPGKWKPKIIGGIGGFVRVKEYD
QVPIEICGHKVIGKVVVGPTPANIIGRNMMTQMGCTLNF

References
Author Title Citation
Mueller, SM Susceptibility to saquinavir and atazanavir in highly protease inhibitor(PI) resistant HIV-1 is caused by lopinavir-induced drug resistance mutation L76V. Antivir Ther, 2004
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005