Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA21008 | CA48325 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T | 52 |
| 2 | 3TC+D4T+RTV | 30 |
| 3 | 3TC+D4T+DDI | 157 |
| 4 | None | 31 |
| 5 | 3TC+D4T+DDI | 74 |
| 6 | 3TC+ABC+DDI | 44 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L63S |
| >CA48325| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QISIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, M184MV | I135T, S162SC, I178M, Q207H, R211K, F214FL, E248EG, A272P, K277R, A288AT, E297T |
| >CA48326| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDMVI YQYVDDLYVGSDLEIGQHRTKIEELRHHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPGKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKTLTEVIPLTTEAE |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |