Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16120 | CA48241 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 80 |
| 2 | D4T+DDI+RTV+SQV | 94 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | G73S | L10I, K20R, E35D, M36I, N37D, R57K, L63P, A71V, I93L |
| >CA48241| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVKQYD QIPIEICGHKVISTVLVGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | K20R, V60I, T69N, K122E, D123N, I135V, I178IM, I195L, G196E, T200TA, E203G, Q207EG, V245K, E248ED, D250DE, A272P, K277R, T286A, G333E, Q367L |
| >CA48242| codons 1-368 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYMDDLYVGSDLELEQHRAKIGELRGHLLRWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIKLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKLL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |