Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7983 | CA48200 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+DDI+IDV | 222 |
| 2 | 3TC+D4T+NFV+NVP | 13 |
| 3 | 3TC+DDI+IDV | 183 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V | K219KE | K101E, Y181C | A98AS, K122E, D123N, I135T, Q174R, I178M, V179I, E194ED, G196E, T200I, L228LR, E248ED, T286A, E297KR |
| >CA48200| codons 1-302 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLEKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPDMII CQYVDDLYVGSDLDIEQHRIKIEELRQHLLRWGFTTPDEKHQKEPPFRWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTREAE LE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | G73S | L10I, I13V, K14R, I15V, K20KM, N37D, K45R, Q61E, I62V, L63P, I66L, A71T, I72R, V77I, I93L, C95V |
| >CA48199| codons 1-99 PQITLWQRPIVTVRVGGQLMEALLDTGADDTVLEEMDLPGRWKPRMIGGIGGFIKVRQYD EVPIELCGHKTRSTVLIGPTPVNVIGRNLMTQLGVTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |