Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6799 | CA48183 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 74 |
| 2 | 3TC+D4T+IDV | 378 |
| 3 | 3TC+DDI+EFV+TDF | 31 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82T, L90M | G73S | L10I, E35D, N37D, K45R, L63P, A71V, I93L |
| >CA48183| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDMDLPGRWKPRIIGGIGGFIKVRQYD QIPIEICGHKVISTVLVGPTPTNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74V, M184V | K219Q | G190E | S48T, T69N, D121Y, K122E, D123E, E169D, D177E, T200A, Q207K, F214L, L283LI, I293V, P294T, E297K |
| >CA48184| codons 2-301 ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKITKIGPENPYNTPVF AIKKKNSNRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLY EEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPEIVIY QYVDDLYVESDLEIGQHRAKIEELRKHLLRWGLTTPDQKHQKEPPFLWMGYELHPDKWTV QPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKALTEVVTLTKEAEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |