Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1595 | CA48119 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | 117 |
| 2 | 3TC+D4T+DDI+EFV+RTV+SQV | 178 |
| 3 | 3TC+D4T+DDI+RTV+SQV | 118 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54A, V82T | L10I, I13V, L19V, K20R, E35D, M36I, N37D, I62V, L63P, I66F, A71I |
| >CA48119| codons 1-99 PQITLWQRPIVTVKIGGQVREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFAKVRQYD QVPIEFCGHKIIGTVLVGPTPTNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, M184V, L210W, T215Y | V108I | V35I, T39A, K43Q, E44D, T107A, L109V, V118I, K122E, D123E, S162C, I178L, V179I, V189I, G196E, H208Y, R211K, A272P, E297Q |
| >CA48120| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEQDGKISKIGPENPYNTPV FAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVAIVDVGDAYFSIPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDLII YQYVDDLYIGSDLEIEQHRTKIEELRQYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTQEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |