Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8040 | CA48108 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ABC+AZT+EFV | 8 |
| 2 | 3TC+ABC+AZT | 31 |
| 3 | 3TC+ABC+AZT+NVP | 133 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74LI, Y115F, M184V, T215F | K219E | K103N | S3C, V35T, V60I, V90I, I94L, S162Y, I167V, E203D, H208Y, V245M, K249Q, A272P, T286A, I293V, P294S |
| >CA48108| codons 1-301 PICPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKIVDFRELNKRTQDFWEIQLGLPHPAGLKKNKSVTVLDVGDAFFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKVLEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIDELRQYLLRWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIMLPEQDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVSLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L33V, I64V |
| >CA48107| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |