Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7920 | CA48102 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | DDI+LPV+NVP | 69 |
| 3 | ABC+DDI+LPV+TDF | 44 |
| 4 | 3TC+APV+D4T+RTV+SQV+TDF | 66 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, L74V, M184V, L210W, T215Y | K219Q | K103N, Y181C | V108I | K20R, V60I, K101Q, K104R, K122KE, I135V, D177E, V189I, H208Y, R211K, D218E, H221Y, L228H, D237N, A272P, L283I, I293V, E297A |
| >CA48102| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKNRSVTILDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYVDDLYIGSDLEIGQHRTKIEELRQYLWKWGFYTPEQKYQKEPPFHWMGYELHPNKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVVPLTAEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, I84V, L90M | L33F, G73S | L10I, I13V, R57K, I62V, L63P, A71T, I72T, V77I, I93L |
| >CA48101| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMNLPGRWKPKIIGGIGGFVKVKQYD QVPIEICGHKTTSTVLIGPTPANVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |