Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8049 | CA48096 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 78 |
| 2 | D4T+DDI+NFV | 135 |
| 3 | D4T+DDI+RTV+SQV | 66 |
| 4 | D4T+DDI+EFV+TDF | 99 |
| 5 | ATV+DDI+RTV+TDF | 5 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | T215I, K219E | G190E | V35L, S48SL, R83K, K101R, K103R, D177E, I178M, D192DG, G196E, T200A, E204N, R211K, L228R, V245E, A272P, T286A, E297K | L205LP |
| >CA48096| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKILKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLRKRKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVESGLEIEQHRAKIENPRQHLLKWGFITPDEKHQKEPPFRWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I54V, L90M | L33I, N88D | I13V, E35D, M36I, N37T, I62V, L63P, A71T |
| >CA48095| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADNTVIEDITLPGRWKPKMIGGIGGFVKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRDLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |