Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patMOU_2 | 00_MOU_2 | France | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT| DDC| D4T| ABC| DDI| EFV| IDV| NFV| RTV| SQV | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82A, I84V | L10I, I13V, G17E, K20I, M36I, D60E, I62V, L63P, A71T |
| >00_MOU_2| codons 1-99 PQITLWQRPIVTVKIGEQLIEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFVKVRQYE QVPIEICGHKTIGTVLVGPTPANVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74V, M184V | T215V, K219Q | L100I, K103N | K20R, K66X, I135V, V179I, I202V, F214L, L228H | K13M |
| >00_MOU_2| codons 1-246 PISPIETVPVKLMPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKTNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVGSDLEIGQHRTKVEELRQHLLRWGLVTPDQKHQKEPPFHWMGYELHPDKWT VQPIVL |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |