Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AC_Pat46 | RO.00.IS.46 | Romania | 2000 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | NA |
| 2 | Unknown | NA |
| 3 | ABC+ 3TC+ NFV+ SQV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M |
| >RO.00.IS.46| codons 1-99 PQITLWQRPLVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QITIDICGHKATGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | V35T, T39A, E40D, D123E, I135L, S162H, K173L, Q174R, I195L, T200A, Q207A, R211T |
| >RO.00.IS.46| codons 33-239 ALTEICADMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQL GIPHPAGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRYQYNVLPQG WKGSPAIFQHSMTKILEPFRLRNPDIVIYQYMDDLYVGSDLELGQHRAKIEELRAHLLTW GFTTPDKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Apetrei, C | HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. | ARHR, 2003 |