Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AC_Pat36 | RO.00.IS.36 | Romania | 2000 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ AZT | NA |
| 2 | None | NA |
| 3 | NVP+ RTV+ D4T | NA |
| 4 | NFV+ SQV+ 3TC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | K103N | V35T, T39A, E40D, D123E, I135L, S162Y, K173I, Q174K, T200A, Q207E, R211K | Y232H |
| >RO.00.IS.36| codons 33-239 ALTEICADMEKEGKISKIGPENPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQL GIPHPAGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRYQYNVLPQG WKGSPAIFQYSMTKILEPFRIKNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELREHLLKW GFTTPDKKHQKEPPFLWMGHELHPDKW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, K70E, I72T, L89M |
| >RO.00.IS.36| codons 1-99 PQITLWQRPVVIVKVEGQLREALLDTGADDTVLEDINLPGKWKPKLIGGIGGFVKVKQYD QVTIDICGHEATGTVLVGPTPANIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Apetrei, C | HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. | ARHR, 2003 |