Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AC_Pat23 | RO.00.IS.23 | Romania | 2000 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ AZT | NA |
| 2 | None | NA |
| 3 | IDV+ NVP+ AZT | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R | K219Q | K103N, Y181C | V35T, T39A, E40D, V60I, D123E, I135L, S162H, K173A, Q174K, I195L, Q197K, T200A, Q207T, R211K, L228H |
| >RO.00.IS.23| codons 33-239 ALTEICADMEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQL GIPHPAGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRYQYNVLPQG WKGSPAIFQHSMTKILEPFRAKNPDIVICQYMDDLYVGSDLELGKHRAKIEELRTHLLKW GFTTPDQKHQKEPPFHWMGYELHPDKW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A | I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72T, L89M |
| >RO.00.IS.23| codons 1-99 PQITLWQRPLVTIKVEGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QITIDICGHKATGTVLVGPTPANIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Apetrei, C | HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. | ARHR, 2003 |